TargetMol

SMP-028

Product Code:
 
TAR-T12936
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12936-5mg5mg£850.00
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Quantity:
TAR-T12936-50mg50mg£1,661.00
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Quantity:
TAR-T12936-100mg100mg£2,079.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
SMP-028 is a neutral cholesterol esterase (CEase) inhibitor(IC50 : 1.01 μM).
CAS:
914389-14-3
Formula:
C23H26FN5O2S
Molecular Weight:
455.55
Purity:
0.98
SMILES:
CNC(=O)NCCn1c(csc1=N/c1cccc(F)c1)-c1ccc(cc1)N1CCOCC1

References

1. Nishizato Y, et al. Translational research into species differences of endocrine toxicity via steroidogenesis inhibition by SMP-028--for human safety in clinical study. Toxicol Appl Pharmacol. 2014 May 1;276(3):213-9. 2. Nishizato Y, et al. Effect of SMP-028 on steroidogenesis in rats; mechanism of toxicological events on endocrine organs of rats. Toxicol In Vitro. 2014 Apr;28(3):397-402.