TargetMol

Spebrutinib besylate

Product Code:
 
TAR-T14357
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14357-5mg5mg£850.00
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TAR-T14357-50mg50mg£1,661.00
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TAR-T14357-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Spebrutinib besylate (AVL-292 benzenesulfonate; CC-292 besylate) is a Btk kinase activity inhibitor (IC50<0.5 nM, Kinact/Ki=7.69?104 M-1s-1s).
CAS:
1360053-81-1
Formula:
C28H28FN5O6S
Molecular Weight:
581.62
Pathway:
Angiogenesis; Tyrosine Kinase/Adaptors
Purity:
0.98
SMILES:
OS(=O)(=O)c1ccccc1.COCCOc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1
Target:
BTK

References

1. Evans EK, et al. Inhibition of Btk with CC-292 provides early pharmacodynamic assessment of activity in mice and humans. J Pharmacol Exp Ther. 2013 Aug;346(2):219-28.