TargetMol

Napsagatran hydrate

Product Code:
 
TAR-T16273
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16273-5mg5mg£1,251.00
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Quantity:
TAR-T16273-50mg50mg£2,464.00
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Quantity:
TAR-T16273-100mg100mg£3,283.00
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This product comes from: United States.
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Further Information

Bioactivity:
Napsagatran hydrate is a novel and specific inhibitor of thrombin.
CAS:
159668-20-9
Formula:
C26H36N6O7S
Molecular Weight:
576.67
Purity:
0.98
SMILES:
O.NC(=N)N1CCC[C@@H](CNC(=O)C[C@H](NS(=O)(=O)c2ccc3ccccc3c2)C(=O)N(CC(O)=O)C2CC2)C1

References

1. Pratico D, et al. Interaction of a thrombin inhibitor and a platelet GP IIb/IIIa antagonist in vivo: evidence thatthrombin mediates platelet aggregation and subsequent thromboxane A2 formation during coronary thrombolysis. J Pharmacol Exp Ther. 1997 Jun;281(3):1178-85. 2. Lundquist P, et al. Prediction of in vivo rat biliary drug clearance from an in vitro hepatocyte efflux model. Drug Metab Dispos. 2014 Mar;42(3):459-68. 3. Himber J, et al. Inhibition of tissue factor limits the growth of venous thrombus in the rabbit. J Thromb Haemost. 2003 May;1(5):889-95.