TargetMol

N-Boc-4-pentyne-1-amine

Product Code:
 
TAR-T18391
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T18391-500mg500mg£111.00
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Further Information

Bioactivity:
N-Boc-4-pentyne-1-amine is a PROTAC linker, which refers to the alkyl chain composition. N-Boc-4-pentyne-1-amine can be used in the synthesis of the PROTAC MG-277[1].
CAS:
151978-50-6
Formula:
C10H17NO2
Molecular Weight:
183.251
Pathway:
Others|PROTAC
Purity:
0.98
SMILES:
CC(C)(C)OC(=O)NCCCC#C
Target:
Others|PROTAC Linker

Documents

References

1. Yang J, et al. Simple Structural Modifications Converting a Bona fide MDM2 PROTAC Degrader into a Molecular Glue Molecule: A Cautionary Tale in the Design of PROTAC Degraders. J Med Chem. 2019 Oct 21.