Clocortolone

Product Code:

TAR-T21374

Product Group:

Inhibitors and Activators

Supplier:

TargetMol

Regulatory Status:

RUO

Shipping:

cool pack

Storage:

-20℃

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Code	Size	Price

TAR-T21374-25mg

25mg

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Further Information

Bioactivity:

Clocortolone is a Corticosteroid Hormone Receptor Agonist. It is used in the form of an ester, clocortolone pivalate, and applied as a cream. clocortolone pivalate is used to treat dermatitis and is considered a medium-strength corticosteroid.

CAS:

4828-27-7

Formula:

C22H28ClFO4

Molecular Weight:

410.91

Purity:

0.98

SMILES:

C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@H]1C(=O)CO

Documents

References

1. Del Rosso JQ, Kircik LH. Transitioning from brand to generic with topical products and the importance of maintaining the formulation and therapeutic profiles of the original product: focus on clocortolone pivalate 0.1% cream. J Drugs Dermatol. 2014 Jul;13(7):s77-83. PubMed PMID: 25007376. 2. Kircik LH. A study to assess the occlusivity and moisturization potential of three topical corticosteroid products using the skin trauma after razor shaving (STARS) bioassay. J Drugs Dermatol. 2014 May;13(5):582-5. PubMed PMID: 24809882. 3. Del Rosso JQ, Kircik LH. The role of a midpotency topical corticosteroid and the clinical relevance of formulation characteristics in the management of commonly encountered eczematous and inflammatory dermatoses in adults and children: focus on the pharmacologic properties of clocortolone pivalate 0.1% cream. J Drugs Dermatol. 2013 Feb;12(2):s5-s10. PubMed PMID: 23377405. 4. Kircik LH. Clocortolone pivalate: a topical corticosteroid with a unique structure. J Drugs Dermatol. 2013 Feb;12(2):s3-4. PubMed PMID: 23377404.