TargetMol

ASP-6537

Product Code:
 
TAR-T23758
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T23758-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T23758-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T23758-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
ASP-6537 is a selective and reversible inhibitor of cyclooxygenase-1.
CAS:
524699-72-7
Formula:
C17H17N3O3
Molecular Weight:
311.341
Purity:
0.98
SMILES:
COc1nc(-c2ccc(OC)cc2)n(n1)-c1ccc(OC)cc1

References

1. Sakata C, Suzuki KI, Morita Y, Kawasaki T. Additive antithrombotic effect of ASP6537, a selective cyclooxygenase (COX)-1 inhibitor, in combination with clopidogrel in guinea pigs. Eur J Pharmacol. 2017 Mar 5;798:72-76. doi: 10.1016/j.ejphar.2017.01.015. Epub 2017 Jan 14. PubMed PMID: 28095326. 2. Ofosu FA. Effective, selective and specific inhibition of COX-1 may overcome the "aspirin paradox". Thromb Res. 2013 Jul;132(1):1-2. doi: 10.1016/j.thromres.2013.04.011. Epub 2013 May 7. PubMed PMID: 23664562. 3. Sakata C, Kawasaki T, Kato Y, Abe M, Suzuki K, Ohmiya M, Funatsu T, Morita Y, Okada M. ASP6537, a novel highly selective cyclooxygenase-1 inhibitor, exerts potent antithrombotic effect without "aspirin dilemma". Thromb Res. 2013 Jul;132(1):56-62. doi: 10.1016/j.thromres.2013.03.005. Epub 2013 Mar 22. PubMed PMID: 23522855. 4. Imanishi J, Morita Y, Yoshimi E, Kuroda K, Masunaga T, Yamagami K, Kuno M, Hamachi E, Aoki S, Takahashi F, Nakamura K, Miyata S, Ohkubo Y, Mutoh S. Pharmacological profile of FK881(ASP6537), a novel potent and selective cyclooxygenase-1 inhibitor. Biochem Pharmacol. 2011 Oct 1;82(7):746-54. doi: 10.1016/j.bcp.2011.06.035. Epub 2011 Jul 2. PubMed PMID: 21745460.