TargetMol

Aspergillomarasmine A

Product Code:
 
TAR-T23759
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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TAR-T23759-5mg5mg£850.00
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Further Information

Bioactivity:
Aspergillomarasmine A is a polyamine acid naturally produced by the mold Aspergillus Versicolor.
CAS:
3484-65-9
Formula:
C10H17N3O8
Molecular Weight:
307.259
Purity:
0.98
SMILES:
NC(CNC(CN[C@@H](CC(O)=O)C(O)=O)C(O)=O)C(O)=O

References

1. Zhang J, Wang S, Bai Y, Guo Q, Zhou J, Lei X. Total Syntheses of Natural Metallophores Staphylopine and Aspergillomarasmine A. J Org Chem. 2017 Dec 15;82(24):13643-13648. doi: 10.1021/acs.joc.7b02342. Epub 2017 Nov 30. PubMed PMID: 29115130. 2. Bergstrom A, Katko A, Adkins Z, Hill J, Cheng Z, Burnett M, Yang H, Aitha M, Mehaffey MR, Brodbelt JS, Tehrani KHME, Martin NI, Bonomo RA, Page RC, Tierney DL, Fast W, Wright GD, Crowder MW. Probing the Interaction of Aspergillomarasmine A with Metallo-?-lactamases NDM-1, VIM-2, and IMP-7. ACS Infect Dis. 2018 Feb 9;4(2):135-145. doi: 10.1021/acsinfecdis.7b00106. Epub 2017 Nov 9. PubMed PMID: 29091730; PubMed Central PMCID: PMC5807211. 3. Zhang J, Wang S, Wei Q, Guo Q, Bai Y, Yang S, Song F, Zhang L, Lei X. Synthesis and biological evaluation of Aspergillomarasmine A derivatives as novel NDM-1 inhibitor to overcome antibiotics resistance. Bioorg Med Chem. 2017 Oct 1;25(19):5133-5141. doi: 10.1016/j.bmc.2017.07.025. Epub 2017 Jul 14. PubMed PMID: 28784300. 4. Dolgin E. Inner Workings: Combating antibiotic resistance from the ground up. Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):11642-11643. PubMed PMID: 27791044; PubMed Central PMCID: PMC5081612.