TargetMol

P505-15 Acetate

Product Code:
 
TAR-T24584
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24584-1mg1mg£227.00
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TAR-T24584-5mg5mg£431.00
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TAR-T24584-1mL1 mL * 10 mM (in DMSO)£483.00
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TAR-T24584-10mg10mg£600.00
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TAR-T24584-25mg25mg£863.00
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TAR-T24584-50mg50mg£1,187.00
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Quantity:
TAR-T24584-100mg100mg£1,581.00
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Quantity:
TAR-T24584-500mg500mg£3,107.00
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This product comes from: United States.
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Further Information

Bioactivity:
P505-15 Acetate is a selective inhibitor of spleen tyrosine kinase that acts by suppressing leukocyte immune function and inflammation and leading to a reduction in arthritis score and attenuated histological damage.
CAS:
1370261-98-5
Formula:
C21H27N9O3
Molecular Weight:
453.5
Pathway:
Proteases/Proteasome
Purity:
0.98
SMILES:
O=C(C1=CN=C(N[C@H]2[C@@H](N)CCCC2)N=C1NC3=CC=CC(N4N=CC=N4)=C3)N.CC(O)=O
Target:
Tyrosinase

References

1. Coffey G, DeGuzman F, Inagaki M, Pak Y, Delaney SM, Ives D, Betz A, Jia ZJ, Pandey A, Baker D, Hollenbach SJ, Phillips DR, Sinha U. Specific inhibition of spleen tyrosine kinase suppresses leukocyte immune function and inflammation in animal models of rheumatoid arthritis. J Pharmacol Exp Ther. 2012 Feb;340(2):350-9. doi: 10.1124/jpet.111.188441. Epub 2011 Oct 31. PubMed PMID: 22040680.