TargetMol

PAFAH1b2

Product Code:
 
TAR-T24586
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24586-5mg5mg£571.00
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Quantity:
TAR-T24586-50mg50mg£1,661.00
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Quantity:
TAR-T24586-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
PAFAH1b2 is a selective platelet-activating factor acetylhydrolases 1b2 and 1b3 inhibitor that acts by impairing cancer cell survival.
CAS:
942285-55-4
Formula:
C30H33NO4S
Molecular Weight:
503.66
Purity:
0.98
SMILES:
Cc1ccc(cc1)[C@H]1CC=C([C@H](N1S(=O)(=O)c1ccc(C)cc1)c1ccc(cc1)C(C)(C)C)C(O)=O

References

1. Liu H, Wang H, Hongmei Z, Zhang H, Liu S. Preliminary Study of Protein Changes in Trisomy 21 Fetus by Proteomics Analysis in Amniocyte. Prenat Diagn. 2018 Apr 2. doi: 10.1002/pd.5259. [Epub ahead of print] PubMed PMID: 29611199. 2. Ding X, Lu J, Yu R, Wang X, Wang T, Dong F, Peng B, Wu W, Liu H, Geng Y, Zhang R, Ma H, Cheng J, Yu M, Fang S. Preliminary Proteomic Analysis of A549 Cells Infected with Avian Influenza Virus H7N9 and Influenza A Virus H1N1. PLoS One. 2016 May 25;11(5):e0156017. doi: 10.1371/journal.pone.0156017. eCollection 2016. PubMed PMID: 27223893; PubMed Central PMCID: PMC4880285. 3. Sarma BK, Liu X, Kodadek T. Identification of selective covalent inhibitors of platelet activating factor acetylhydrolase 1B2 from the screening of an oxadiazolone-capped peptoid-azapeptoid hybrid library. Bioorg Med Chem. 2016 Sep 1;24(17):3953-3963. doi: 10.1016/j.bmc.2016.04.047. Epub 2016 Apr 23. PubMed PMID: 27160052; PubMed Central PMCID: PMC4972644. 4. Gombojav B, Lee SJ, Kho M, Song YM, Lee K, Sung J. Multiple susceptibility loci at chromosome 11q23.3 are associated with plasma triglyceride in East Asians. J Lipid Res. 2016 Feb;57(2):318-24. doi: 10.1194/jlr.P063461. Epub 2015 Dec 3. PubMed PMID: 26634697; PubMed Central PMCID: PMC4727427.