TargetMol

PARPi-FL

Product Code:
 
TAR-T24597
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24597-5mg5mg£850.00
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Further Information

Bioactivity:
PARPi-FL is an agent of fluorescent PARP imaging. In vitro, it is capable of detecting the target engagement of a PARP inhibitor panel.
CAS:
1380359-84-1
Formula:
C34H32BF3N6O3
Molecular Weight:
640.47
Purity:
0.98
SMILES:
CC1=CC(C)=[N+]2C1=Cc1ccc(CCC(=O)N3CCN(CC3)C(=O)c3cc(Cc4n[nH]c(=O)c5ccccc45)ccc3F)n1[B-]2(F)F

References

1. Zhang J. Poly (ADP-ribose) polymerase inhibitor: an evolving paradigm in the treatment of prostate cancer. Asian J Androl. 2014 May-Jun;16(3):401-6. doi: 10.4103/1008-682X.123684. Review. PubMed PMID: 24589464; PubMed Central PMCID: PMC4023365. 2. Shackelford RE, Mayhall K, Maxwell NM, Kandil E, Coppola D. Nicotinamide phosphoribosyltransferase in malignancy: a review. Genes Cancer. 2013 Nov;4(11-12):447-56. doi: 10.1177/1947601913507576. Review. PubMed PMID: 24386506; PubMed Central PMCID: PMC3877665. 3. Mason KA, Raju U, Buchholz TA, Wang L, Milas ZL, Milas L. Poly (ADP-ribose) polymerase inhibitors in cancer treatment. Am J Clin Oncol. 2014 Feb;37(1):90-100. doi: 10.1097/COC.0b013e3182467dce. Review. PubMed PMID: 22495455. 4. Ismail-Khan R, Bui MM. A review of triple-negative breast cancer. Cancer Control. 2010 Jul;17(3):173-6. Review. PubMed PMID: 20664514.