TargetMol

Umespirone

Product Code:
 
TAR-T24923
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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  • Further Information
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Further Information

Bioactivity:
Umespirone is a potential antipsychotic/anxiolytic drug of the azapirone class. It possesses anxiolytic and antipsychotic properties.
CAS:
107736-98-1
Formula:
C28H40N4O5
Molecular Weight:
512.651
Purity:
0.98
SMILES:
CCCCN1C(=O)C2C(=O)N(CCCCN3CCN(CC3)c3ccccc3OC)C(=O)C(C1=O)C2(C)C

Documents

References

1. D?molis JL, Martel C, Funck-Brentano C, Sachse A, Weimann HJ, Jaillon P. Effects of tedisamil, atenolol and their combination on heart and rate-dependent QT interval in healthy volunteers. Br J Clin Pharmacol. 1997 Oct;44(4):403-9. PubMed PMID: 9354317; PubMed Central PMCID: PMC2042860. 2. Hohnloser SH, Dorian P, Straub M, Beckmann K, Kowey P. Safety and efficacy of intravenously administered tedisamil for rapid conversion of recent-onset atrial fibrillation or atrial flutter. J Am Coll Cardiol. 2004 Jul 7;44(1):99-104. PubMed PMID: 15234416. 3. van Haarst AD, Dijkmans AC, Weimann HJ, Kemme MJ, Bosch JJ, Schoemaker RC, Cohen AF, Burggraaf J. Clinically important interaction between tedisamil and verapamil. J Clin Pharmacol. 2009 May;49(5):560-7. doi: 10.1177/0091270009332812. Epub 2009 Mar 19. PubMed PMID: 19299533. 4. Mitrovic V, Miskovic A, Strau M, Thormann J, Pitschner H, Hamm C. Hemodynamic, antiischemic, and neurohumoral effects of tedisamil and atenolol in patients with coronary artery disease. Cardiovasc Drugs Ther. 2000 Oct;14(5):511-21. PubMed PMID: 11101199.