TargetMol

ETB067

Product Code:
 
TAR-T25394
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T25394-5mg5mg£850.00
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Quantity:
TAR-T25394-50mg50mg£1,661.00
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Quantity:
TAR-T25394-100mg100mg£2,079.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
ETB067, an H-89 analog, acts as a PKA and AKT1 inhibitor with specificity on no longer inhibiting CAMK2B and neither affecting viability of mice nor causing any detectable tissue damage at the dose given.
CAS:
1000995-79-8
Formula:
C21H22BrN3O2S
Molecular Weight:
460.39
Purity:
0.98
SMILES:
CC(CNCCNS(=O)(=O)c1cccc2cnccc12)=C/c1ccc(Br)cc1

References

1. Guo J, Parise RA, Joseph E, Egorin MJ, Lazo JS, Prochownik EV, Eiseman JL. Efficacy, pharmacokinetics, tisssue distribution, and metabolism of the Myc-Max disruptor, 10058-F4 [Z,E]-5-[4-ethylbenzylidine]-2-thioxothiazolidin-4-one, in mice. Cancer Chemother Pharmacol. 2009 Mar;63(4):615-25. doi: 10.1007/s00280-008-0774-y. Epub 2008 May 29. PubMed PMID: 18509642; PubMed Central PMCID: PMC2752825.