TargetMol

HEPT

Product Code:
 
TAR-T25493
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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  • Further Information
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Further Information

Bioactivity:
HEPT is a non-nucleoside inhibitor of HIV-1 reverse transcription.
CAS:
123027-56-5
Formula:
C14H16N2O4S
Molecular Weight:
308.35
Purity:
0.98
SMILES:
Cc1c(Sc2ccccc2)n(COCCO)c(=O)[nH]c1=O

Documents

References

1. Nuter F, Dim? AK, Chen C, Bounaadja L, Mouray E, Florent I, Six Y, Buriez O, Marinetti A, Voituriez A. Access to new endoperoxide derivatives by electrochemical oxidation of substituted 3-azabicyclo[4.1.0]hept-4-enes. Chemistry. 2015 Mar 27;21(14):5584-93. doi: 10.1002/chem.201406138. Epub 2015 Feb 20. PubMed PMID: 25703453. 2. Hudkins RL, Becknell NC, Lyons JA, Aimone LD, Olsen M, Haltiwanger RC, Mathiasen JR, Raddatz R, Gruner JA. 3,4-Diaza-bicyclo[4.1.0]hept-4-en-2-one phenoxypropylamine analogs of irdabisant (CEP-26401) as potent histamine-3 receptor inverse agonists with robust wake-promoting activity. Eur J Med Chem. 2015 May 5;95:349-56. doi: 10.1016/j.ejmech.2015.03.054. Epub 2015 Mar 24. PubMed PMID: 25827402. 3. Scognamiglio J, Letizia CS, Api AM. Fragrance material review on 1-(3,3-dimethylbicyclo[2.2.1]hept-2-yl)ethane-1-one. Food Chem Toxicol. 2013 Dec;62 Suppl 1:S110-4. doi: 10.1016/j.fct.2013.08.058. Review. PubMed PMID: 24246178. 4. Zhu S, Ren L, Yu S, Gong C, Song D, Zheng G. Enzymatic preparation of optically pure (+)-2-azabicyclo[2.2.1]hept-5-en-3-one by (-)-?-lactamase from Bradyrhizobium japonicum USDA 6. Bioorg Med Chem Lett. 2014 Oct 15;24(20):4899-902. doi: 10.1016/j.bmcl.2014.08.057. Epub 2014 Sep 2. PubMed PMID: 25240615.