TargetMol

Rhizocticin A

Product Code:
 
TAR-T26074
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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Further Information

Bioactivity:
Rhizocticin A is a potential inhibitor of threonine synthase.
CAS:
114301-25-6
Formula:
C11H22N5O6P
Molecular Weight:
351.3
Purity:
0.98
SMILES:
N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C=C/CP(O)(O)=O)C(O)=O

References

1. Gahungu M, Arguelles-Arias A, Fickers P, Zervosen A, Joris B, Damblon C, Luxen A. Synthesis and biological evaluation of potential threonine synthase inhibitors: Rhizocticin A and Plumbemycin A. Bioorg Med Chem. 2013 Sep 1;21(17):4958-67. doi: 10.1016/j.bmc.2013.06.064. Epub 2013 Jul 8. PubMed PMID: 23891162. 2. Kugler M, Loeffler W, Rapp C, Kern A, Jung G. Rhizocticin A, an antifungal phosphono-oligopeptide of Bacillus subtilis ATCC 6633: biological properties. Arch Microbiol. 1990;153(3):276-81. PubMed PMID: 2110446. 3. Kino K, Kotanaka Y, Arai T, Yagasaki M. A novel L-amino acid ligase from Bacillus subtilis NBRC3134, a microorganism producing peptide-antibiotic rhizocticin. Biosci Biotechnol Biochem. 2009 Apr 23;73(4):901-7. Epub 2009 Apr 7. PubMed PMID: 19352016. 4. Kino K. [Novel L-amino acid ligases catalyzing oligopeptide synthesis]. Yakugaku Zasshi. 2010 Nov;130(11):1463-9. Review. Japanese. PubMed PMID: 21048404.