TargetMol

Romazarit

Product Code:
 
TAR-T26118
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26118-5mg5mg£850.00
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TAR-T26118-50mg50mg£1,661.00
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Quantity:
TAR-T26118-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Romazarit, a propionic acid derivative, is used as a PPARα agonist and acts as an antirheumatic drug.
CAS:
109543-76-2
Formula:
C15H16ClNO4
Molecular Weight:
309.75
Purity:
0.98
SMILES:
Cc1nc(oc1COC(C)(C)C(O)=O)-c1ccc(Cl)cc1

References

1. Bloxham DP, Bradshaw D, Cashin CH, Dodge BB, Lewis EJ, Westmacott D, Self CR. Biologic properties of romazarit (Ro 31-3948), a potential disease-modifying antirheumatic drug. J Pharmacol Exp Ther. 1990 Mar;252(3):1331-40. PubMed PMID: 2156999. 2. Holford NH, Williams PE, Muirhead GJ, Mitchell A, York A. Population pharmacodynamics of romazarit. Br J Clin Pharmacol. 1995 Mar;39(3):313-20. PubMed PMID: 7619674; PubMed Central PMCID: PMC1365009. 3. Williams PE, Muirhead GJ, Worth E, Zimmer R, L?cker P. Pharmacokinetics and tolerance of romazarit after oral administration of ascending single doses to healthy human volunteers. Eur J Drug Metab Pharmacokinet. 1990 Oct-Dec;15(4):317-22. PubMed PMID: 2088768. 4. Williams PE, Bird HA, Minty S, Helliwell PS, Muirhead GJ, Bentley J, York A. A pharmacokinetic and tolerance study of romazarit in patients with rheumatoid arthritis. Biopharm Drug Dispos. 1992 Mar;13(2):119-29. PubMed PMID: 1550907.