TargetMol

RU 33965

Product Code:
 
TAR-T26149
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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  • Further Information
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Further Information

Bioactivity:
RU 33965, a 3-cyclopropyl carbonyl imidazobenzodiazepine, act as a low-efficacy benzodiazepine receptor inverse agonist.
CAS:
122321-05-5
Formula:
C16H15N3O2
Molecular Weight:
281.315
Purity:
0.98
SMILES:
CN1Cc2c(ncn2-c2ccccc2C1=O)C(=O)C1CC1

Documents

References

1. Gardner CR, Budhram P, Parker FL. Discriminative stimulus properties of RU 33965, a benzodiazepine receptor weak partial inverse agonist. Pharmacol Biochem Behav. 1992 Oct;43(2):583-8. PubMed PMID: 1359581. 2. Ward RA, Gardner CR, Pringle A, Bagust J, Walker RJ. The effects of RU 33965 and RU 34030, two new 3-cyclopropyl carbonyl imidazobenzodiazepines, on GABAA receptor-mediated synaptic transmission in cerebellar slices in the rat. Gen Pharmacol. 1994 May;25(3):589-97. PubMed PMID: 7926610. 3. Turchi J, Holley LA, Sarter M. Effects of benzodiazepine receptor inverse agonists and nicotine on behavioral vigilance in senescent rats. J Gerontol A Biol Sci Med Sci. 1996 May;51(3):B225-31. PubMed PMID: 8630700. 4. McGaughy J, Sarter M. Behavioral vigilance in rats: task validation and effects of age, amphetamine, and benzodiazepine receptor ligands. Psychopharmacology (Berl). 1995 Feb;117(3):340-57. PubMed PMID: 7770610.