TargetMol

Rubratoxin B

Product Code:
 
TAR-T26165
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T26165-5mg5mg£850.00
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Further Information

Bioactivity:
Rubratoxin B is a mycotoxin that causes hypoglycemia and fatty liver and has exhibited anticancer activity.
CAS:
21794-01-4
Formula:
C26H30O11
Molecular Weight:
518.515
Purity:
0.98
SMILES:
CCCCCCC(O)C1C(O)C2=C(CC(CC3=C1C(=O)OC3=O)C(O)C1CC=CC(=O)O1)C(=O)OC2=O

References

1. Nagashima H. Rubratoxin-B-induced secretion of chemokine ligands of cysteine-cysteine motif chemokine receptor 5 (CCR5) and its dependence on heat shock protein 90 in HL60 cells. Environ Toxicol Pharmacol. 2015 Nov;40(3):997-1000. doi: 10.1016/j.etap.2015.10.012. Epub 2015 Nov 2. PubMed PMID: 26595743. 2. Iwashita K, Nagashima H. Rubratoxin B induces signs of fatty acid oxidation disorders (FAODs) in mice. Toxicol Lett. 2011 Oct 10;206(2):238-43. doi: 10.1016/j.toxlet.2011.07.027. Epub 2011 Jul 30. PubMed PMID: 21835235. 3. Nagashima H, Nakamura K, Goto T. Hepatotoxin rubratoxin B induced the secretion of TNF-alpha, IL-8, and MCP-1 in HL60 cells. Biochem Biophys Res Commun. 2001 Oct 5;287(4):829-32. PubMed PMID: 11573937. 4. Iwashita K, Nagashima H. Rubratoxin B induces interleukin-6 secretion in mouse white adipose tissues and 3T3-L1 adipocytes. Toxicol Lett. 2008 Nov 10;182(1-3):79-83. doi: 10.1016/j.toxlet.2008.08.008. Epub 2008 Aug 29. PubMed PMID: 18804154.