TargetMol

EO-122

Product Code:
 
TAR-T27272
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27272-5mg5mg£850.00
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TAR-T27272-50mg50mg£1,661.00
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Quantity:
TAR-T27272-100mg100mg£2,079.00
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Further Information

Bioactivity:
EO-122, a calcium channel antagonist and sodium channel antagonist, is used potentially for the treatment of arrhythmia.
CAS:
23581-62-6
Formula:
C16H23ClN2O
Molecular Weight:
294.82
Purity:
0.98
SMILES:
Cl.Cc1cccc(C)c1NC(=O)C1CN2CCC1CC2

References

1. Oppenheimer E, Harel G, Lipinsky D, Sarne Y. EO-199, a specific antagonist of antiarrhythmic drugs: assessment by binding experiments and in vivo studies. Life Sci. 1991;48(10):977-85. PubMed PMID: 2000027. 2. Oppenheimer E, Meiri H, Ori Y. The specific binding of [3H]EO-122, a radiolabeled class I antiarrhythmic drug to rat heart membranes. J Mol Cell Cardiol. 1989 Feb;21(2):223-30. Erratum in: J Mol Cell Cardiol 1989 Dec;21(12):1356. PubMed PMID: 2545887. 3. Marrer S. [Molecular modeling of anti-arrhythmia agents in class Ia and Ib--model conceptions of different binding receptors]. Pharm Acta Helv. 1989;64(12):338-44. German. PubMed PMID: 2616583. 4. Binah O, Gilat E, Rubinstein I, Oppenheimer E. Electrophysiological effects of a novel antiarrhythmic drug, EO-122, on guinea pig ventricular muscle and isolated myocytes. J Cardiovasc Pharmacol. 1987 Sep;10(3):301-8. PubMed PMID: 2444778.