TargetMol

Eremomycin

Product Code:
 
TAR-T27280
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T27280-25mg25mgEnquire
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Further Information

Bioactivity:
Eremomycin, an antibiotic, can be used intramuscularly due to low toxicity.
CAS:
110865-90-2
Formula:
C73H91ClN10O26
Molecular Weight:
1560.03
Purity:
0.98
SMILES:
CN[C@H](CC(C)C)C(=O)N[C@@H]1[C@H](O)c2ccc(Oc3cc4cc(OC5=CC=C(CC5)[C@@H](O[C@H]5C[C@](C)(N)[C@@H](O)[C@H](C)O5)[C@@H]5NC(=O)[C@@H](NC(=O)[C@@H]4NC(=O)[C@H](CC(N)=O)NC1=O)c1ccc(O)c(c1)-c1c(O)cc(O)cc1[C@H](NC5=O)C(O)=O)c3O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O[C@H]1C[C@](C)(N)[C@@H](O)[C@H](C)O1)c(Cl)c2

Documents

References

1. Bychkova EN, Korolev AM, Olsufyeva EN, Mirchink EP, Isakova EB. [Design of Novel Carboxamides of Eremomycin and Vancomycin with 4- or 3-Amino Methyl Phenyl Boric Acid and Their Investigation]. Antibiot Khimioter. 2015;60(9-10):7-11. Russian. PubMed PMID: 27141632. 2. Nikitina YK, Ali I, Asnin LD. Adsorption of aqueous organic mixtures on a chiral stationary phase with bound antibiotic eremomycin. J Chromatogr A. 2014 Oct 10;1363:71-8. doi: 10.1016/j.chroma.2014.08.062. Epub 2014 Aug 26. PubMed PMID: 25182859. 3. Chang J, Zhou H, Preobrazhenskaya M, Tao P, Kim SJ. The Carboxyl Terminus of Eremomycin Facilitates Binding to the Non-d-Ala-d-Ala Segment of the Peptidoglycan Pentapeptide Stem. Biochemistry. 2016 Jun 21;55(24):3383-91. doi: 10.1021/acs.biochem.6b00188. Epub 2016 Jun 7. PubMed PMID: 27243469. 4. Miroshnikova OV, Berdnikova TF, Olsufyeva EN, Pavlov AY, Reznikova MI, Preobrazhenskaya MN, Ciabatti R, Malabarba A, Colombo L. A modification of the N-terminal amino acid in the eremomycin aglycone. J Antibiot (Tokyo). 1996 Nov;49(11):1157-61. PubMed PMID: 8982345.