TargetMol

F-901318

Product Code:
 
TAR-T27300
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27300-1mg1mg£384.00
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Quantity:
TAR-T27300-5mg5mg£815.00
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Quantity:
TAR-T27300-10mg10mg£1,083.00
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Quantity:
TAR-T27300-25mg25mg£1,556.00
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Quantity:
TAR-T27300-50mg50mg£1,902.00
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Quantity:
TAR-T27300-100mg100mg£2,319.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
F-901318 is a DHODH inhibitor.
CAS:
1928707-56-5
Formula:
C28H27FN6O2
Molecular Weight:
498.562
Purity:
0.98
SMILES:
Cc1cc(c(C(=O)C(=O)Nc2ccc(cc2)N2CCN(CC2)c2ncc(F)cn2)n1C)-c1ccccc1

References

1. Oliver JD, Sibley GE, Beckmann N, Dobb KS, Slater MJ, McEntee L, du Pr? S, Livermore J, Bromley MJ, Wiederhold NP, Hope WW, Kennedy AJ, Law D, Birch M. F901318 represents a novel class of antifungal drug that inhibits dihydroorotate dehydrogenase. Proc Natl Acad Sci U S A. 2016 Oct 25. pii: 201608304. [Epub ahead of print] PubMed PMID: 27791100; PubMed Central PMCID: PMC5111691. 2. Seyedmousavi S, Rafati H, Ilkit M, Tolooe A, Hedayati MT, Verweij P. Systemic Antifungal Agents: Current Status and Projected Future Developments. Methods Mol Biol. 2017;1508:107-139. PubMed PMID: 27837500. 3. Osherov N, Kontoyiannis DP. The anti-Aspergillus drug pipeline: Is the glass half full or empty? Med Mycol. 2017 Jan 1;55(1):118-124. PubMed PMID: 27562862.