TargetMol

IMTPPE

Product Code:
 
TAR-T27601
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T27601-100mg100mgEnquire
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TAR-T27601-50mg50mgEnquire
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
IMTPPE inhibits transcriptional activity and protein level of AR in C4-2 prostate cancer cells. It also inhibits AR-target gene expression.
CAS:
851688-13-6
Formula:
C20H27N3O2S
Molecular Weight:
373.52
Purity:
0.98
SMILES:
Cc1noc(C)c1CSCC(=O)N1CCN(CC1)c1cccc(C)c1C

Documents

References

1. Masoodi KZ, Eisermann K, Yang Z, Dar JA, Pascal LE, Nguyen M, O'Malley K, Parrinello E, Feturi FG, Kenefake AN, Nelson JB, Johnston PA, Wipf P, Wang Z. Inhibition of Androgen Receptor Function and Level in Castration-Resistant Prostate Cancer Cells by 2-[(isoxazol-4-ylmethyl)thio]-1-(4-phenylpiperazin-1-yl)ethanone. Endocrinology. 2017 Oct 1;158(10):3152-3161. doi: 10.1210/en.2017-00408. PubMed PMID: 28977599; PubMed Central PMCID: PMC5659684.