TargetMol

Indolapril hydrochloride

Product Code:
 
TAR-T27608
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27608-5mg5mg£850.00
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TAR-T27608-50mg50mg£1,661.00
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Quantity:
TAR-T27608-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Indolapril hydrochloride is a nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity.
CAS:
80828-32-6
Formula:
C24H35ClN2O5
Molecular Weight:
467
Purity:
0.98
SMILES:
Cl.[H][C@]12C[C@H](N(C(=O)[C@H](C)N[C@@H](CCc3ccccc3)C(=O)OCC)[C@@]1([H])CCCC2)C(O)=O

References

1. Blankley CJ, Kaltenbronn JS, DeJohn DE, Werner A, Bennett LR, Bobowski G, Krolls U, Johnson DR, Pearlman WM, Hoefle ML, et al. Synthesis and structure-activity relationships of potent new angiotensin converting enzyme inhibitors containing saturated bicyclic amino acids. J Med Chem. 1987 Jun;30(6):992-8. PubMed PMID: 3035180. 2. La Rocca PT, Squibb RE, Powell ML, Szot RJ, Black HE, Schwartz E. Acute and subchronic toxicity of a nonsulfhydryl angiotensin-converting enzyme inhibitor. Toxicol Appl Pharmacol. 1986 Jan;82(1):104-11. PubMed PMID: 3003964. 3. Roark WH, Tinney FJ, Cohen D, Essenburg AD, Kaplan HR. Synthesis and biological activity of modified peptide inhibitors of angiotensin-converting enzyme. J Med Chem. 1985 Sep;28(9):1291-5. PubMed PMID: 2993618. 4. Brunner HR, Nussberger J, Waeber B. The present molecules of converting enzyme inhibitors. J Cardiovasc Pharmacol. 1985;7 Suppl 1:S2-11. Review. PubMed PMID: 2580170.