TargetMol

INF55

Product Code:
 
TAR-T27609
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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  • Further Information
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Further Information

Bioactivity:
INF55 inhibits NorA efflux pump.
CAS:
4993-87-7
Formula:
C14H10N2O2
Molecular Weight:
238.246
Purity:
0.98
SMILES:
[O-][N+](=O)c1ccc2[nH]c(cc2c1)-c1ccccc1

Documents

References

1. Dolla NK, Chen C, Larkins-Ford J, Rajamuthiah R, Jagadeesan S, Conery AL, Ausubel FM, Mylonakis E, Bremner JB, Lewis K, Kelso MJ. On the Mechanism of Berberine-INF55 (5-Nitro-2-phenylindole) Hybrid Antibacterials. Aust J Chem. 2015;67:1471-1480. PubMed PMID: 26806960; PubMed Central PMCID: PMC4720975. 2. Liger F, Bouhours P, Ganem-Elbaz C, Jolivalt C, Pellet-Rostaing S, Popowycz F, Paris JM, Lemaire M. C2 Arylated Benzo[b]thiophene Derivatives as Staphylococcus aureus NorA Efflux Pump Inhibitors. ChemMedChem. 2016 Feb 4;11(3):320-30. doi: 10.1002/cmdc.201500463. Epub 2016 Jan 6. PubMed PMID: 26732895. 3. Wang S, Yu J, Suvira M, Setlow P, Li YQ. Uptake of and Resistance to the Antibiotic Berberine by Individual Dormant, Germinating and Outgrowing Bacillus Spores as Monitored by Laser Tweezers Raman Spectroscopy. PLoS One. 2015 Dec 4;10(12):e0144183. doi: 10.1371/journal.pone.0144183. eCollection 2015. PubMed PMID: 26636757; PubMed Central PMCID: PMC4670213. 4. Ayg?l A. [The importance of efflux systems in antibiotic resistance and efflux pump inhibitors in the management of resistance]. Mikrobiyol Bul. 2015 Apr;49(2):278-91. Review. Turkish. PubMed PMID: 26167829.