TargetMol

iNUB

Product Code:
 
TAR-T27615
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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  • Further Information
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Further Information

Bioactivity:
iNUB is a NEMO-Ub binding inhibitor. iNUB inhibits TNFα induced NF-κB signaling and has selectively toxic to IKK/NF-κB dependent ABC-DLBCL.
CAS:
352336-00-6
Formula:
C24H16O5
Molecular Weight:
384.387
Purity:
0.98
SMILES:
Oc1cccc2C(=O)c3cccc(OC(=O)C4CC4c4ccccc4)c3C(=O)c12

Documents

References

1. Alert R, Tierno P, Casademunt J. Mixed-order phase transition in a colloidal crystal. Proc Natl Acad Sci U S A. 2017 Dec 5;114(49):12906-12909. doi: 10.1073/pnas.1712584114. Epub 2017 Nov 20. PubMed PMID: 29158388; PubMed Central PMCID: PMC5724272. 2. Guc M, Hariskos D, Calvo-Barrio L, Jackson P, Oliva F, Pistor P, Perez-Rodriguez A, Izquierdo-Roca V. Resonant Raman scattering based approaches for the quantitative assessment of nanometric ZnMgO layers in high efficiency chalcogenide solar cells. Sci Rep. 2017 Apr 25;7(1):1144. doi: 10.1038/s41598-017-01381-4. PubMed PMID: 28442796; PubMed Central PMCID: PMC5430671. 3. Gonz?lez-Castillo C, Ortu?o-Sahag?n D, Guzm?n-Brambila C, M?rquez-Aguirre AL, Raisman-Vozari R, Pall?s M, Rojas-Mayorqu?n AE. The absence of pleiotrophin modulates gene expression in the hippocampus in vivo and in cerebellar granule cells in vitro. Mol Cell Neurosci. 2016 Sep;75:113-21. doi: 10.1016/j.mcn.2016.07.004. Epub 2016 Jul 26. PubMed PMID: 27468976. 4. S?nchez-Huertas C, Freixo F, Viais R, Lacasa C, Soriano E, L?ders J. Non-centrosomal nucleation mediated by augmin organizes microtubules in post-mitotic neurons and controls axonal microtubule polarity. Nat Commun. 2016 Jul 13;7:12187. doi: 10.1038/ncomms12187. PubMed PMID: 27405868; PubMed Central PMCID: PMC4947180.