TargetMol

LUF7346

Product Code:
 
TAR-T27863
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T27863-100mg100mgEnquire
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TAR-T27863-50mg50mgEnquire
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Further Information

Bioactivity:
LUF7346 is an allosteric modulator of hERG.
CAS:
1821638-40-7
Formula:
C20H15BrN2O3
Molecular Weight:
411.255
Purity:
0.98
SMILES:
Brc1ccccc1C(=O)c1ccc(OCC(=O)Nc2cccnc2)cc1

Documents

References

1. Sala L, Yu Z, Ward-van Oostwaard D, van Veldhoven JP, Moretti A, Laugwitz KL, Mummery CL, IJzerman AP, Bellin M. A new hERG allosteric modulator rescues genetic and drug-induced long-QT syndrome phenotypes in cardiomyocytes from isogenic pairs of patient induced pluripotent stem cells. EMBO Mol Med. 2016 Sep 1;8(9):1065-81. doi: 10.15252/emmm.201606260. Print 2016 Sep. PubMed PMID:27470144; PubMed Central PMCID: PMC5009811.