TargetMol

MJN228

Product Code:
 
TAR-T28050
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T28050-10mg10mgEnquire
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TAR-T28050-1mg1mgEnquire
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TAR-T28050-25mg25mgEnquire
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  • Further Information
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Further Information

Bioactivity:
MJN228 is a selective ligand for the lipid-binding protein nucleobindin 1 (NUCB1). MJN228 blocks binding of the probe arachidonoyl ethanolamide-diazirine with an IC50 value of 3.3 ?M. MJN228 prevents probe binding to NUCB1 in Neuro2a cells at concentrations as low as 10 ?M.
CAS:
459168-97-9
Formula:
C20H20N4O3
Molecular Weight:
364.405
Purity:
0.98
SMILES:
CN1CCN(CC1)C(=O)c1[nH]c2ccc(cc2c1-c1ccccc1)[N+]([O-])=O

Documents

References

1. M. J. Niphakis, K. M. Lum, A. B. Cognetta, III, et al. A global map of the lipid-binding proteins and their ligandability in cells. Cell 161, 1668-1680 (2015).