TargetMol

TASP0376377

Product Code:
 
TAR-T28925
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
TASP0376377 is a potent antagonist of CRTH2.
CAS:
1233246-60-0
Formula:
C25H16Cl2N2O4
Molecular Weight:
479.31
Purity:
0.98
SMILES:
OC(=O)Cc1cnc(C(=O)c2ccc(NC(=O)c3ccc(Cl)c(Cl)c3)cc2)c2ccccc12

Documents

References

1. Nishikawa-Shimono R, Sekiguchi Y, Koami T, Kawamura M, Wakasugi D, Watanabe K, Wakahara S, Kimura K, Yamanobe S, Takayama T. Isoquinoline derivatives as potent CRTH2 antagonists: design, synthesis and SAR. Bioorg Med Chem. 2013 Dec 15;21(24):7674-85. doi: 10.1016/j.bmc.2013.10.025. Epub 2013 Oct 30. PubMed PMID: 24216094. 2. Nishikawa-Shimono R, Sekiguchi Y, Koami T, Kawamura M, Wakasugi D, Watanabe K, Wakahara S, Matsumoto K, Takayama T. Isoquinoline derivatives as potent CRTH2 receptor antagonists: synthesis and SAR. Bioorg Med Chem Lett. 2012 May 1;22(9):3305-10. doi: 10.1016/j.bmcl.2012.03.009. Epub 2012 Mar 10. PubMed PMID: 22469703.