TargetMol

NSC 660028

Product Code:
 
TAR-T33746
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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Further Information

Bioactivity:
NSC 660028 is a novel γ-lactone ring modified arylamino etoposide analogram with strong antitumor activity as an inhibitor of human DNA topoisomerase II.
CAS:
153230-81-0
Formula:
C27H27NO6
Molecular Weight:
461.514
Purity:
0.98
SMILES:
[H][C@@]12COC[C@@]1([H])[C@@H](c1cc(OC)c(O)c(OC)c1)c1cc3OCOc3cc1[C@@H]2Nc1ccccc1

Documents

References

Zhou XM, Lee KJ, Cheng J, Wu SS, Chen HX, Guo X, Cheng YC, Lee KH. Antitumor agents. 144. New gamma-lactone ring-modified arylamino etoposide analogs as inhibitors of human DNA topoisomerase II. J Med Chem. 1994 Jan 21;37(2):287-92. PubMed PMID: 8295216.