TargetMol

ST-1006

Product Code:
 
TAR-T34709
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T34709-1mg1mg£352.00
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TAR-T34709-1mL1 mL * 10 mM (in DMSO)£630.00
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TAR-T34709-5mg5mg£736.00
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TAR-T34709-10mg10mg£978.00
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TAR-T34709-25mg25mg£1,348.00
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TAR-T34709-50mg50mg£1,661.00
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Quantity:
TAR-T34709-100mg100mg£2,079.00
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Quantity:
TAR-T34709-500mg500mg£4,006.00
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Further Information

Bioactivity:
ST-1006 is a histamine H4 receptor, which can relieve neuropathic pain through differential regulation of ERK, JNK, and p38 MAPK phosphorylation.
CAS:
1196994-11-2
Formula:
C16H20Cl2N6
Molecular Weight:
367.28
Pathway:
Neuroscience|GPCR/G Protein|Immunology/Inflammation
Purity:
0.98
SMILES:
CN1CCN(CC1)c1cc(NCc2c(Cl)cccc2Cl)nc(N)n1
Target:
Histamine Receptor

References

Sanna MD, et al. Histamine H4 receptor activation alleviates neuropathic pain through differential regulation of ERK, JNK, and P38 MAPK phosphorylation. Pain. 2015;156(12):2492-504. Mommert S, et al. Human basophil chemotaxis and activation are regulated via the histamine H4 receptor. Allergy. 2016;71(9):1264-1273. Ehling S, et al. Allergic inflammation is augmented via histamine H4 receptor activation: The role of natural killer cells in vitro and in vivo. J Dermatol Sci. 2016;83(2):106-115. Lucarini L, et al. Role of histamine H4 receptor ligands in bleomycin-induced pulmonary fibrosis. Pharmacol Res. 2016;111:740-748. Adami M, et al. Differential effects of functionally different histamine H4 receptor ligands on acute irritant dermatitis in mice. Naunyn Schmiedebergs Arch Pharmacol. 2018;391(12):1387-1397.