TargetMol

Trimetoquinol HCl hydrate

Product Code:
 
TAR-T34950
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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Further Information

Bioactivity:
Trimetoquinol hydrochloride possesses differential and selective beta-adrenergic properties.
CAS:
72534-66-8
Formula:
C19H26ClNO6
Molecular Weight:
399.87
Purity:
0.98
SMILES:
O.Cl.COc1cc(C[C@@H]2NCCc3cc(O)c(O)cc23)cc(OC)c1OC

Documents

References

Miller DD, Osei-Gyimah P, Raman RV, Feller DR. Synthesis of 1-substituted analogues of trimetoquinol possessing differential and selective beta-adrenergic properties. J Med Chem. 1977 Nov;20(11):1502-4. PubMed PMID: 21293. Himori N, Taira N. Assessment of the selectivity of OPC-2009, a new beta2-adrenoceptor stimulatn, by the use of the blood-perfused trachea in situ and of the isolated blood-perfused papillary muscle of the dog. Br J Pharmacol. 1977 Sep;61(1):9-17. PubMed PMID: 21014; PubMed Central PMCID: PMC1667687. Nishi H, Fukuyama T, Matsuo M, Terabe S. Chiral separation of diltiazem, trimetoquinol and related compounds by micellar electrokinetic chromatography with bile salts. J Chromatogr. 1990 Aug 31;515:233-43. PubMed PMID: 2283364. Ikezawa K, Narita H, Ikeo T, Umino N, Iwakuma T, Sato M. [Bronchodilating and cardiovascular actions of (-)-1-(3, 4, 5-trimethoxybenzyl)-5, 7-dihydroxy-1, 2, 3, 4-tetrahydroisoquinoline hydrochloride (l-DTI) in the anesthetized dog (author's transl)]. Nihon Yakurigaku Zasshi. 1978 Sep;74(6):663-70. Japanese. PubMed PMID: 711026.