TargetMol

T0070907

Product Code:
 
TAR-T6689
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T6689-5mg5mg£107.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6689-1mL1 mL * 10 mM (in DMSO)£111.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6689-10mg10mg£113.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6689-25mg25mg£145.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6689-50mg50mg£191.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6689-100mg100mg£237.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6689-200mg200mg£287.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
T0070907(IC50=1 nM) , an effective and specific PPARγ inhibitor, with the >800-fold selectivity over PPARα and PPARδ.
CAS:
313516-66-4
Formula:
C12H8ClN3O3
Molecular Weight:
277.66
Pathway:
DNA Damage/DNA Repair; Metabolism
Purity:
0.9936
SMILES:
[O-][N+](=O)c1ccc(Cl)c(c1)C(=O)Nc1ccncc1
Target:
PPAR

References

Zaytseva YY et al. Anticancer Res, 2011, 31(3), 813-823. Collin M et al. Crit Care Med, 2006, 34(4), 1131-1138. Lee G et al. J Biol Chem, 2002, 277(22), 19649-19657. Ren Q, Xie X, Zhao C, et al. 2, 2?, 4, 4?-Tetrabromodiphenyl Ether (PBDE 47) Selectively Stimulates Proatherogenic PPAR? Signatures in Human THP-1 Macrophages to Contribute to Foam Cell Formation. Chemical Research in Toxicology. 2022