TargetMol

NI-57

Product Code:
 
TAR-TQ0083
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TQ0083-1mg1mg£98.00
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TAR-TQ0083-5mg5mg£132.00
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TAR-TQ0083-1mL1 mL * 10 mM (in DMSO)£142.00
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TAR-TQ0083-10mg10mg£174.00
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TAR-TQ0083-25mg25mg£302.00
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TAR-TQ0083-50mg50mg£434.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
NI-57 is an inhibitor of proteins of bromodomain and plant homeodomain finger-containing (BRPF) family, with IC50s of 3.1, 46 and 140 nM for BRPF1, BRPF2 (BRD1) and BRPF3, respectively.
CAS:
1883548-89-7
Formula:
C19H17N3O4S
Molecular Weight:
383.42
Pathway:
Chromatin/Epigenetic
Purity:
1
SMILES:
COc1cc(ccc1S(=O)(=O)Nc1ccc2n(C)c(=O)c(C)cc2c1)C#N
Target:
Epigenetic Reader Domain

Documents

References

Igoe N, et al. Design of a Chemical Probe for the Bromodomain and Plant Homeodomain Finger-Containing (BRPF) Family of Proteins. J Med Chem. 2017 Aug 24;60(16):6998-7011.