TargetMol

10,12-Tricosadiynoic acid

Product Code:
 
TAR-T10035
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10035-10mg10mg£103.00
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Quantity:
TAR-T10035-25mg25mg£124.00
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TAR-T10035-50mg50mg£144.00
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Quantity:
TAR-T10035-100mg100mg£164.00
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This product comes from: United States.
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Further Information

Bioactivity:
10,12-Tricosadiynoic acid is a highly selective and orally active inhibitor of acyl-CoA oxidase-1 (ACOX1). It can treat the high-fat diet- or obesity-induced metabolic diseases by improving mitochondrial lipid and ROS metabolism.
CAS:
66990-30-5
Formula:
C23H38O2
Molecular Weight:
346.555
Pathway:
Metabolism
Purity:
0.98
SMILES:
CCCCCCCCCCC#CC#CCCCCCCCCC(O)=O
Target:
Acyltransferase

References

1. Zeng J, et al. Specific Inhibition of Acyl-CoA Oxidase-1 by an Acetylenic Acid Improves Hepatic Lipid and Reactive Oxygen Species (ROS) Metabolism in Rats Fed a High Fat Diet. J Biol Chem. 2017 Mar 3;292(9):3800-3809.