TargetMol

AZD9567

Product Code:
 
TAR-T14386
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14386-1mg1mg£241.00
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TAR-T14386-5mg5mg£503.00
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TAR-T14386-1mL1 mL * 10 mM (in DMSO)£547.00
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TAR-T14386-10mg10mg£695.00
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TAR-T14386-25mg25mg£1,018.00
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TAR-T14386-50mg50mg£1,348.00
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Quantity:
TAR-T14386-100mg100mg£1,781.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
AZD9567 (compound 15) is a potent, oral active, non-steroidal and selective glucocorticoid receptor modulator (SGRM), with an IC50 of 3.8 nM. It shows excellent efficacy in the streptococcal cell wall (SCW) reactivation model of joint inflammation[1].
CAS:
1893415-00-3
Formula:
C27H28F2N4O3
Molecular Weight:
494.543
Pathway:
Endocrinology/Hormones
Purity:
0.98
SMILES:
CC(C)[C@H](NC(=O)C(C)(F)F)[C@H](Oc1ccc2n(ncc2c1)-c1ccc(=O)n(C)c1)c1ccccc1
Target:
Glucocorticoid Receptor

Documents

References

1. Ripa L, et al. Discovery of a Novel Oral Glucocorticoid Receptor Modulator (AZD9567) with Improved Side Effect Profile. J Med Chem. 2018 Mar 8;61(5):1785-1799.