N-Nitroso-N-methyl-4-Aminobutyric Acid
Code | Size | Price |
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TAR-T36415-10mg | 10mg | £225.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T36415-25mg | 25mg | £441.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T36415-50mg | 50mg | £775.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T36415-100mg | 100mg | £1,246.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
N-Nitroso-N-methyl-4-aminobutyric acid (NMBA) is a tobacco-specific nitrosamine carcinogen.1It is oxidized to the reactive metabolite methyl-2-oxopropylnitrosamine (MOPN) in isolated rat liver mitochondria.2NMBA induces bladder transitional cell carcinomas in rats when administered in the drinking water at a concentration of 300 mg/L per day.3
CAS:
61445-55-4
Formula:
C5H10N2O3
Molecular Weight:
146.146
Purity:
0.98
SMILES:
CN(CCCC(O)=O)N=O
References
Lijinsky, W., Reuber, M.D., Saavedra, J.E., et al.Carcinogenesis in F344 rats by N-nitrosomethyl-n-propylamine derivativesJ. Natl. Cancer Inst.70(5)959-963(1983)
Djordjevic, M.V., Brunnemann, K.D., and Hoffmann, D.Identification and analysis of a nicotine-derived N-nitrosamino acid and other nitrosamino acids in tobaccoCarcinogenesis10(9)1725-1731(1989)
Janzowski, C., Landsiedel, R., G?lzer, P., et al.Mitochondrial formation of ?-oxopropyl metabolites from bladder carcinogenic ?-carboxyalkylnitrosaminesChem. Biol. Interact.90(1)23-33(1994)