TargetMol

Zuclopenthixol

Product Code:
 
TAR-T4117
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4117-25mg25mg£95.00
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TAR-T4117-50mg50mg£102.00
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TAR-T4117-1mL1 mL * 10 mM (in DMSO)£105.00
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TAR-T4117-100mg100mg£115.00
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TAR-T4117-200mg200mg£135.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
Zuclopenthixol is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors.
CAS:
53772-83-1
Formula:
C22H25ClN2OS
Molecular Weight:
400.97
Pathway:
Neuroscience; GPCR/G Protein
Purity:
0.9996
SMILES:
OCCN1CCN(CCC=C2c3ccccc3Sc3ccc(Cl)cc23)CC1
Target:
Dopamine Receptor

Documents

References

Khalifa AE: Zuclopenthixol facilitates memory retrieval in rats: possible involvement of noradrenergic and serotonergic mechanisms. Pharmacol Biochem Behav. 2003 Jul;75(4):755-62. Fond G, Macgregor A, Tamouza R, Hamdani N, Meary A, Leboyer M, Dubremetz JF: Comparative analysis of anti-toxoplasmic activity of antipsychotic drugs and valproate. Eur Arch Psychiatry Clin Neurosci. 2013 Jun 15. Jayakody K, Gibson RC, Kumar A, Gunadasa S: Zuclopenthixol acetate for acute schizophrenia and similar serious mental illnesses. Cochrane Database Syst Rev. 2012 Apr 18;4:CD20200525. doi: 10.12002/14651858.CD20200525.pub3. Hood S, Orr K, Bennett L, Davies S: Severe laryngeal dystonia in a patient receiving zuclopenthixol "Acuphase" and fluoxetine. Australas Psychiatry. 2010 Apr;18(2):174-6. doi: 10.3109/103198560903473686 Nielsen MK, Johansen SS: Simultaneous determination of 25 common pharmaceuticals in whole blood using ultra-performance liquid chromatography-tandem mass spectrometry. J Anal Toxicol. 2012 Sep;36(7):497-506. doi: 10.1093/jat/bks054. Epub 2012 Jun 19.