TargetMol

SEC inhibitor KL-2

Product Code:
 
TAR-T16868
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16868-1mg1mg£138.00
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TAR-T16868-1mL1 mL * 10 mM (in DMSO)£225.00
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TAR-T16868-5mg5mg£282.00
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TAR-T16868-10mg10mg£436.00
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TAR-T16868-25mg25mg£658.00
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TAR-T16868-50mg50mg£863.00
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Quantity:
TAR-T16868-100mg100mg£1,139.00
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Quantity:
TAR-T16868-500mg500mg£2,223.00
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Further Information

Bioactivity:
SEC inhibitor KL-2 (KL-2) is a potent, selective super elongation complex (SEC) inhibitor. SEC inhibitor KL-2 exhibits a dose-dependent inhibitory effect on AFF4-CCNT1 interaction (Ki: 1.50 μM).
CAS:
900308-51-2
Formula:
C17H13ClFNO3
Molecular Weight:
333.74
Purity:
0.98
SMILES:
Cc1ccc(Cl)cc1NC(=O)C(O)=CC(=O)c1ccc(F)cc1

References

1. Liang K, et al. Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced CancerTherapy. Cell. 2018 Oct 18;175(3):766-779.