TargetMol

Tauroursodeoxycholate sodium

Product Code:
 
TAR-T6993
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6993-25mg25mg£95.00
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TAR-T6993-50mg50mg£104.00
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TAR-T6993-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T6993-100mg100mg£117.00
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TAR-T6993-200mg200mg£132.00
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TAR-T6993-500mg500mg£166.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
Tauroursodeoxycholate Sodium is an endoplasmic reticulum (ER) stress inhibitor, used for the treatment of gallstones and liver cirrhosis.
CAS:
35807-85-3
Formula:
C26H44NNaO6S
Molecular Weight:
521.69
Pathway:
MAPK; Apoptosis; Proteases/Proteasome
Purity:
0.9978
SMILES:
[Na+].C[C@H](CCC(=O)NCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3[C@@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
Target:
Apoptosis; ERK; Caspase

Documents

References

Alpini G, et al. Am J Physiol Gastrointest Liver Physiol. 2004, 286(6), G973-982. Che J, Lv H, Yang J, et al. Iron overload induces apoptosis of osteoblast cells via eliciting ER stress-mediated mitochondrial dysfunction and p-eIF2?/ATF4/CHOP pathway in vitro. Cellular Signalling. 2021 Aug;84:110024. doi: 10.1016/j.cellsig.2021.110024. Epub 2021 Apr 24. Che J, Lv H, Yang J, et al. Iron overload induces apoptosis of osteoblast cells via eliciting ER stress-mediated mitochondrial dysfunction and p-eIF2?/ATF4/CHOP pathway in vitro[J]. Cellular Signalling. 2021: 110024. Sommerfeld A, et al. Cell Physiol Biochem. 2015, 36(3), 866-883. Milkiewicz P, et al. J Hepatol. 2001, 34(2), 184-191. Luo R, Li L, Liu X, et al. Mesenchymal stem cells alleviate palmitic acid induced endothelial to mesenchymal transition by suppressing endoplasmic reticulum stress[J]. American Journal of Physiology-Endocrinology and Metabolism. 2020 Luo R, Li L, Liu X, et al. Mesenchymal stem cells alleviate palmitic acid-induced endothelial-to-mesenchymal transition by suppressing endoplasmic reticulum stress[J]. American Journal of Physiology-Endocrinology and Metabolism. 2020, 319(6): E961-E980. Luo R, Li L, Liu X, et al. Mesenchymal stem cells alleviate palmitic acid induced endothelial to mesenchymal transition by suppressing endoplasmic reticulum stress. American Journal of Physiology-Endocrinology and Metabolism. 2020 Ishizaki K, et al. Eur J Pharmacol. 2001, 421(1), 55-60.