TargetMol

HSL-IN-1

Product Code:
 
TAR-T11576
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
HSL-IN-1 is an orally active hormone-sensitive lipase (HSL) inhibitor (IC50: 2 nM) with a significantly reduced reactive metabolite liability.
CAS:
2095156-13-9
Formula:
C19H13BClF3N2O4
Molecular Weight:
436.58
Purity:
0.98
SMILES:
OB(O)c1cc(Cl)ccc1NC(=O)c1ccc(Oc2ccc(cc2)C(F)(F)F)nc1

Documents

References

1. Ogiyama T, et al. Identification of a novel hormone sensitive lipase inhibitor with a reduced potential of reactive metabolites formation. Bioorg Med Chem. 2017 Apr 1;25(7):2234-2243.