TargetMol

AM-4668

Product Code:
 
TAR-T14202
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T14202-100mg100mgEnquire
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  • Further Information
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Further Information

Bioactivity:
AM-4668 is a type 2 diabetes GPR40 agonist. For GPR40, in A9 cells (GPR40 IP3 assay) and CHO cells (GPR40 aequorin assay), the EC50s are 3.6 nM and 36 nM, respectively.
CAS:
1011531-27-3
Formula:
C24H19F3N2O4S
Molecular Weight:
488.48
Pathway:
GPCR/G Protein; Endocrinology/Hormones
Purity:
0.98
SMILES:
Cc1nc(sc1COc1ccc(cc1)[C@H](CC(O)=O)c1ccon1)-c1ccc(cc1)C(F)(F)F
Target:
GPR

Documents

References

1. Liu JJ, et al. Optimization of GPR40 Agonists for Type 2 Diabetes. ACS Med Chem Lett. 2014 Feb 6;5(5):517-21.