TargetMol

N-tert-butyl- α-Phenylnitrone

Product Code:
 
TAR-T23046
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T23046-25mg25mg£99.00
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TAR-T23046-50mg50mg£109.00
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TAR-T23046-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T23046-100mg100mg£128.00
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Quantity:
TAR-T23046-200mg200mg£161.00
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This product comes from: United States.
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Further Information

Bioactivity:
N-tert-butyl-α-Phenylnitrone inhibits COX2 catalytic activity. N-tert-butyl-α-Phenylnitrone possesses potent reactive oxygen species scavenging, anti-inflammatory, neuroprotective, anti-aging, and anti-diabetic activities, and can penetrate the blood-brain barrier.
CAS:
3376-24-7
Formula:
C11H15NO
Molecular Weight:
177.247
Pathway:
Immunology/Inflammation; Neuroscience
Purity:
0.9969
SMILES:
CC(C)(C)[N+]([O-])=Cc1ccccc1
Target:
ROS; COX

References

1. Zhenggang Zhou, et al. PBN Protects NP Cells From AAPH-induced Degenerative Changes by Inhibiting the ERK1/2 Pathway. Connect Tissue Res. 2020 Mar 30;1-10. 2. Lei Zhao, et al. Reactive Oxygen Species Contribute to Lipopolysaccharide-Induced Teratogenesis in Mice. Toxicol Sci. 2008 May;103(1):149-57.