TargetMol

NSC-668036

Product Code:
 
TAR-T28211
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T28211-5mg5mgEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
NSC-668036 is an inhibitor of Dishevelled (Dvl) protein, a key protein in wnt signaling.
CAS:
144678-63-7
Formula:
C21H36N2O9
Molecular Weight:
460.524
Purity:
0.98
SMILES:
CC(C)C(O)C(=O)N([C@@H](C)C(=O)O[C@@H](C(C)C)C(O)=O)C(=O)[C@H](C)NC(=O)OC(C)(C)C

Documents

References

1. Wang C, Dai J, Sun Z, Shi C, Cao H, Chen X, Gu S, Li Z, Qian W, Han X. Targeted inhibition of disheveled PDZ domain via NSC668036 depresses fibrotic process. Exp Cell Res. 2015 Feb 1;331(1):115-22. doi: 10.1016/j.yexcr.2014.10.023. Epub 2014 Nov 5. PubMed PMID: 25445788. 2. Chen X, Deng Y. Simulations of a specific inhibitor of the dishevelled PDZ domain. J Mol Model. 2009 Jan;15(1):91-6. doi: 10.1007/s00894-008-0377-x. Epub 2008 Oct 25. PubMed PMID: 18953581. 3. Shan J, Shi DL, Wang J, Zheng J. Identification of a specific inhibitor of the dishevelled PDZ domain. Biochemistry. 2005 Nov 29;44(47):15495-503. PubMed PMID: 16300398.