Leinco Technologies

Recombinant Rat IL-2

Product Code:
 
LEI-I-279
Product Group:
 
Recombinant Proteins
Host Type:
 
Rat
Regulatory Status:
 
RUO
Shipping:
 
Dry Ice
Storage:
 
Working aliquots of this recombinant protein solution are stable for up to six months at -20°C to -70°C in a manual defrost freezer. Upon thawing in the presence of a carrier protein this recombinant protein can be stored at 2° - 8°C for one month without detectable loss of activity. For long-term storage aliquot and freeze at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles.
 

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CodeSizePrice
LEI-I-279-10ug10 ug£460.00
Quantity:
LEI-I-279-50ug50 ug£1,199.00
Quantity:
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This product comes from: US.
Typical lead time: 14-21 working days.
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Further Information

Format:
This recombinant protein was 0.2 um filtered and is supplied in a solution of sodium acetate (NaOAc) and Glycerol.
Formulation:
This recombinant protein was 0.2 um filtered and is supplied in a solution of sodium acetate (NaOAc) and Glycerol.
Long Description:
IL-2 is a 17.2 kD cytokine signaling protein that is the regulator of the proliferative and suppressive phases of the immune response, and stimulates growth and differentiation of B cells, NK cells, LAK cells, monocytes, and oligodendrocytes. It functions as a primary regulator of T cell homeostasis. Il-2 regulates the activities of white blood cells and plays a role in the immune system via ?self? and ?non-self? discrimination. IL-2 is a prime candidate in immunotherapeutics for both increasing T cell levels/function and for augmenting vaccine-elicited viral-specific T cell responses. IL-2 signal can be transduced via 3 different signaling pathways that include the JAK-STAT, PI3K/Akt/mTOR and MAPK/ERK pathways. Aldesleukin is a form of recombinant interleukin-2 for the treatment of cancers including malignant melanoma and renal cell cancer. Furthermore, there is additional therapeutic potential for IL-2 mAb use with transplants and autoimmune disease.
NCBI Gene:
116562
Purity:
>97% by SDS-PAGE and analyzed by silver stain.
Target:
IL-2

References

1. Schachter, J. et al. (2009) Cytotherapy 11: 206 2. Sodora, DL. et al. (2009) Curr HIV Res. 7: 83 3. Alcocer-Varela, J. et al. (2009) Autoimmun Rev. 9(1):34-9.