Leinco Technologies

Recombinant Rat Leptin

Product Code:
 
LEI-L146
Product Group:
 
Recombinant Proteins
Host Type:
 
Rat
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
 

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CodeSizePrice
LEI-L146-1mg1 mg£398.00
Quantity:
LEI-L146-5mg5 mg£853.00
Quantity:
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This product comes from: US.
Typical lead time: 14-21 working days.
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Further Information

Format:
This recombinant protein was 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 with no calcium, magnesium, or preservatives.
Formulation:
This recombinant protein was 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 with no calcium, magnesium, or preservatives.
Long Description:
Leptin is a neuroendocrine hormone secreted from adipose tissue that plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism. Leptin is one of the most important adipose derived hormones.1 It interacts with six types of receptors and once it binds to OB-Receptor it activates the stat3, which is phosphorylated and travels to the nucleus to effect changes in gene expression. One of the main effects on gene expression is the down-regulation of the expression of endocannabinoids.2 High leptin levels are associated with psoriasis.3
NCBI Gene:
25608
Purity:
>97% by SDS-PAGE and analyzed by silver stain.
Target:
Leptin

References

1. Mantzoros, CS. et al.(2006) Nat Clin Pract Endocrinol Metab. 2: 318 2. Hill, RA. et al.(2002) Int. J. Obes. Relat. Metab. Disord. 26: 1407 3. Chen, YJ. et al.(2008) Arch Derm. 144: 1571