Leinco Technologies

Recombinant Human TL1-A

Product Code:
 
LEI-T227
Product Group:
 
Recombinant Proteins
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
 

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CodeSizePrice
LEI-T227-10ug10 ug£614.00
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Further Information

Format:
This rProtein has been 0.2 um filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 with no calcium, magnesium or preservatives present.
Formulation:
This rProtein has been 0.2 um filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 with no calcium, magnesium or preservatives present.
Long Description:
TNF-ligand-related molecule 1A (TL1A), is an endothelium-derived T cell costimulator and a ligand for tumor necrosis factor receptor superfamily members DR3 and decoy receptor 3.1 TL1A binds to the death-domain receptor (DR)3 and provides costimulatory signals to activated lymphocytes. Through this interaction, TL1A induces secretion of IFN-γ. Blockade of the TL1A/DR3 pathway may offer therapeutic opportunities in Crohn's disease.2
NCBI Gene:
326623
Purity:
>95% by SDS-PAGE and analyzed by silver stain.
Target:
TL1-A

References

1. Wei, P. et al. (2003) J Biol Chem. 278: 39251 2. Cominelli, F. et al. (2006) PNAS 103: 8441 3. Migone, T. et al. (2002) Immunity 16:479