Leinco Technologies

Recombinant Human BMP-13

Product Code:
 
LEI-B423
Product Group:
 
Recombinant Proteins
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
Dry Ice
Storage:
 
Working aliquots of this recombinant protein solution are stable for up to twelve months at -20°C to -70°C in a manual defrost freezer. Upon thawing in the presence of a carrier protein this recombinant protein can be stored at 2° - 8°C for one month without detectable loss of activity. For long-term storage aliquot and freeze at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles.
 

No additional charges, what you see is what you pay! *

CodeSizePrice
LEI-B423-50ug50 ug£665.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: US.
Typical lead time: 14-21 working days.
Contact us for more accurate information.
  • Further Information
  • References
  • Show All

Further Information

Format:
This recombinant protein was 0.2 um filtered and is supplied in a solution of 35% acetonitrile (CH3CN) and 0.1% trifluoroacetic acid (TFA).
Formulation:
This recombinant protein was 0.2 um filtered and is supplied in a solution of 35% acetonitrile (CH3CN) and 0.1% trifluoroacetic acid (TFA).
Long Description:
Bone Morphogenetic Protein-13 (BMP-13) is a member of the transforming growth factor beta (TGF-beta) superfamily of growth factors that may regulate patterning of the ectoderm by interacting with bone morphogenetic proteins and control eye development. The biological actions of BMP-13 remain poorly understood. Expression of BMP-13 is predominantly seen in hypertrophic chondrocytes in regions of endochondral bone formation during development. BMP-13 in post natal articular cartilage suggests that this protein may function in an autocrine/paracrine way to regulate the growth and maintenance of articular cartilage. In addition to this BMP-13 has been shown to induce neotendon/neoligament formation when injected on a collagen carrier subcutaneously or intramuscularly. This indicates that BMP-13 may have therapeutic value for tendon or ligament healing following injury. At the amino acid sequence level, human and mouse GDF-6 are 99% identical. GDF-6 response is mediated by the formation of hetero-oligomeric complexes of type I (BMPR-IB) and type II (BMPR-II or Activin R-II) sereine/threonine kinase receptors, and the activation of Smad proteins.
NCBI Gene:
242316
Purity:
>97% by SDS-PAGE and analyzed by silver stain.
Target:
Bone Morphogenetic Protein-13

References

1. Nakamura, K. et al. (1999) Exp. Cell Res. 250:351