Leinco Technologies

Recombinant Human Betacellulin

Product Code:
 
LEI-B268
Product Group:
 
Recombinant Proteins
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
 

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CodeSizePrice
LEI-B268-10ug10 ug£534.00
Quantity:
LEI-B268-50ug50 ug£1,445.00
Quantity:
LEI-B268-250ug250 ug£2,810.00
Quantity:
LEI-B268-1000ug1000 ug£7,726.00
Quantity:
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This product comes from: US.
Typical lead time: 14-21 working days.
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Further Information

Format:
This recombinant protein was 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 with no calcium, magnesium, or preservatives.
Formulation:
This recombinant protein was 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 with no calcium, magnesium, or preservatives.
Long Description:
Betacellulin, also known as BTC, is a member of the EGF family of cytokines. BTC is initially synthesized as a glycosylated transmembrane precursor protein, which is processed by proteolytic cleavage to produce the mature sequence (1). Several tissues including kidney, liver, pancreas, uterus, small intestine as well as certain tumor cells express BTC (2). In addition, it can also be found in bodily fluids including serum, milk and colostrum (3). BTC is a potent mitogen for retinal pigment epithelial cells, vascular smooth muscle cells and fibroblasts (4). It also promotes pancreatic beta-cell growth and differentiation (5). The primary receptor for BTC is the receptor for EGF, specifically ErbB-1 and ErbB-4 (6).
NCBI Gene:
685
Purity:
>97% by SDS-PAGE and analyzed by silver stain.
Target:
Betacellulin

References

1. Tada, H. et al. (1999) J. Cell Biochem. 72:423 2. Shing, Y. et al. (1993) Science 259:1604 3. Bastian, SE. et al. (2001) J. Endocrnol. 168:203 4. Dunbar, A. J. et al. (2000) J. Biochem. Cell Bio. 32:805 5. Li, L. et al. (2001) Endocrinology 142:5379 6. Watanabe, T. et al. (1994) J. Biol. Chem. 269:9966