Leinco Technologies

Recombinant Human PDGF Rβ

Product Code:
 
LEI-P254
Product Group:
 
Recombinant Proteins
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
 

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LEI-P254-100ug100 ug£659.00
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This product comes from: US.
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Further Information

Format:
This recombinant protein was 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 with no calcium, magnesium, or preservatives.
Formulation:
This recombinant protein was 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 with no calcium, magnesium, or preservatives.
Long Description:
Platelet-derived growth factor receptor-β (PDGFRβ) is a well-characterized plasma membrane receptor with endogeneous tyrosine kinase activity, which is autophosphorylated in response to binding of dimeric platelet-derived growth factor (PDGF) ligand.1 PDGFRβ mediates signaling important for the proliferation, migration, and survival of mesenchymal cells.2 PDGFRβ is found in all cell types 3 and is activated in breast carcinoma cells and indicate a possible role of the receptor in breast cancerogenesis.4
NCBI Gene:
5159
Purity:
>97% by SDS-PAGE and analyzed by silver stain.
Target:
PDGF R beta

References

1. Gilliland, DG. et al. (1996) Proc Natl Acad Sci USA 93: 14845 2. Ronnstrand, L et al. (1998) Biochim Biophys Acta 1378: F79 3. Fischer, B. et al. (1997) Acta Anatomica 159: 194 4. Valius, M. et al. (2005) Biologija 1: 61