Leinco Technologies

Recombinant Human SMAC

Product Code:
 
LEI-S574
Product Group:
 
Recombinant Proteins
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
2-8°C
Storage:
 
This protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution this protein may be stored at 2°C to 8°C for one week or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
 

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LEI-S574-100ug100 ug£659.00
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This product comes from: US.
Typical lead time: 14-21 working days.
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Further Information

Format:
This recombinant protein was 0.2 um filtered and is supplied in a solution of 20 mM Hepes and 0.1 M potassium chloride (KCl), pH 7.5.
Formulation:
This recombinant protein was 0.2 um filtered and is supplied in a solution of 20 mM Hepes and 0.1 M potassium chloride (KCl), pH 7.5.
Long Description:
Second Mitochondria Derived Activator of Caspase (SMAC) is a mitochondrial apoptogenic protein that is released to the cytosol in response to diverse apoptotic stimuli, including commonly used chemotherapeutic drugs.1 SMAC promotes cytochrome-c dependent activation by eliminating the inhibition of IAP - a protein that negatively regulates apoptosis or programmed cell death.2
NCBI Gene:
56616
Purity:
>95% by SDS-PAGE and analyzed by silver stain.
Target:
SMAC

References

1. Melendez-Zajgla, J. et al. (2008) J Exp Clin Cancer Res. 26: 27 2. Vucic, D. et al. (2002) J Biol chem. 277: 12275