Leinco Technologies

Recombinant Human GDF-15

Product Code:
 
LEI-G640
Product Group:
 
Recombinant Proteins
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
 

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CodeSizePrice
LEI-G640-25ug25 ug£603.00
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This product comes from: US.
Typical lead time: 14-21 working days.
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  • Further Information
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Further Information

Long Description:
Growth differentiation factor 15 (GDF15) is a protein belonging to the transforming growth factor beta superfamily that has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes.1 GDF15 is also known as TGF-PL, MIC-1, PDF, PLAB, and PTGFB.2 GDF15 is predominantly expressed in the liver, with lower levels seen in some other tissues. Its expression in the liver is significantly up-regulated during injury of organs such as liver, kidney, heart and lung.1,2,3 GDF-15 is a promising new biomarker in idiopathic pulmonary arterial hypertension.4
NCBI Gene:
9518
Purity:
>97% by SDS Page and analyzed by silver stain.
Target:
GDF-15

References

1. Koniaris, L. et al. (2005) Shock 23: 543 2. Lee, S. et al. (2000) Mol Cell Biol 20: 3742 3. Sadoshima, J. et al. (2006) Circ Res 98 : 294 4. Wollert KC. et al. (2008)Am J Respir Crit Cre Med. 178 : 534